Next Generation Genomics

Transcriptomics:

RNA-seq

Interactomes:

ChIP-seq: Chromosome Immunoprecipitation then directly to sequencing

CLIP-seq: Cross Linking Immunoprecipitation, like ChIP-seq but with RNA

3C, 4C and 5C: Chromosome Configuration Capture (3C) (Circularized, 4C), etc.

ChIA-PET: Chromosome Interactions through Paired End Tag sequences.

E-MAPS: epistatic miniarray profiles

Epigenomics:

Reduced representation bisulfite sequencing.

MeDIP-seq: like ChIP-seq but with antibodies to methylated DNA.

MethylC-seq: shotgun sequencing of bisulfite-coverted DNA

And there is and will be more, more, more...

Dr. Jeffery Young, Western Washington University